Correction: Transcription Factors Bind Thousands of Active and Inactive Regions in the Drosophila Blastoderm
نویسندگان
چکیده
1600 July 2008 | Volume 6 | Issue 7 | e190 Correction: Transcription Factors Bind Thousands of Active and Inactive Regions in the Drosophila Blastoderm Xiao-yong Li, Stewart MacArthur, Richard Bourgon, David Nix, Daniel A. Pollard, Venky N. Iyer, Aaron Hechmer, Lisa Simirenko, Mark Stapleton, Cris L. Luengo Hendriks, Hou Cheng Chu, Nobuo Ogawa, William Inwood, Victor Sementchenko, Amy Beaton, Richard Weiszmann, Susan E. Celniker, David W. Knowles, Tom Gingeras, Terence P. Speed, Michael B. Eisen, Mark D. Biggin
منابع مشابه
Transcription Factors Bind Thousands of Active and Inactive Regions in the Drosophila Blastoderm
Identifying the genomic regions bound by sequence-specific regulatory factors is central both to deciphering the complex DNA cis-regulatory code that controls transcription in metazoans and to determining the range of genes that shape animal morphogenesis. We used whole-genome tiling arrays to map sequences bound in Drosophila melanogaster embryos by the six maternal and gap transcription facto...
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In animals, each sequence-specific transcription factor typically binds to thousands of genomic regions in vivo. Our previous studies of 20 transcription factors show that most genomic regions bound at high levels in Drosophila blastoderm embryos are known or probable functional targets, but genomic regions occupied only at low levels have characteristics suggesting that most are not involved i...
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The Drosophila genes knirps (kni) and knirps-related (knrl) are located within the 77E1,2 region on the left arm of the third chromosome. They encode nuclear hormone-like transcription factors containing almost identical Cys2/Cys2 DNA-binding zinc finger motifs which bind to the same target sequence. kni is a member of the gap class of segmentation genes, and its activity is required for the no...
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The Drosophila gap gene Krüppel (Kr) encodes a transcriptional regulator. It acts both as an integral part of the Drosophila segmentation gene in the early blastoderm and in a variety of tissues and organs at later stages of embryogenesis. In transfected tissue culture cells, the Kr protein (Kr) was shown to both activate and repress gene expression in a concentration-dependent manner when acti...
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ورودعنوان ژورنال:
- PLoS Biology
دوره 6 شماره
صفحات -
تاریخ انتشار 2008